The Generalist

@nicholas/the-generalist

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Inside Substack’s $650M Playbook for the Future of Media (Chris Best & Hamish McKenzie, Co-Founders)
Done
Lessons from 20 Years of Venture Capital (Roelof Botha, Managing Partner & Steward at Sequoia Capital)
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How AI Will Enhance Human Potential, Not Replace It (Reid Hoffman)
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When Science Fiction Becomes Reality (Josh Wolfe, Co-Founder of Lux Capital)
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Introducing The Generalist Podcast
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Creating Stars in a Bottle: The Race to Commercialize Fusion Energy (Vinod Khosla & Bob Mumgaard)
Done
How Anduril Is Reimagining the Defense Industry: Faster Tech, Ethical AI, and a New Kind of Deterrence (Trae Stephens, Co-Founder & Executive Chairman of Anduril)
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Antimemetics: Why Some Ideas Resist Spreading (Nadia Asparouhova, Writer & Researcher)
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Are We Alone In The Universe? Sara Seager on Exoplanets, Venus, and the Hunt for Alien Life (Astrophysicist and Planetary Scientist at MIT)
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The Semiconductor Century with Chris Miller (Author of “Chip War”)
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Existential Risk and the Future of Humanity: Lessons from AI, Pandemics, and Nuclear Threats (Toby Ord, Author of "The Precipice")
Done
Why the Real Computer Revolution Never Happened (Alan Kay & Anjan Katta)
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No Rivals
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The Decade of Data (Tomasz Tunguz)
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Inside General Catalyst’s $1B+ Bet on Fixing Healthcare (Hemant Taneja, CEO & Managing Partner)
Done
The Future of Crypto: Stablecoins, AI Integration, and the Path to Mass Adoption (Jesse Walden, Founder & Managing Partner at Variant)
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AI Agents Are Here: What They Can Already Do—and What’s Next (Stanislas Polu & Harrison Chase)
Done
Reviving Forgotten Technologies: How Airships, Supersonic Flight, and Geothermal Energy Could Transform Our World (Eli Dourado, Head of Strategic Investments at Astera Institute)
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What Makes Something Alive? Assembly Theory and the Origins of Life (Sara Walker, Theoretical Physicist)
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Building Beautiful Homes with Robots: The Future of Construction (Salar al Khafaji, CEO & Founder of Monumental)
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Inside Substack’s $650M Playbook for the Future of Media (Chris Best & Hamish McKenzie, Co-Founders)

@nicholas1h ago

POD

Lessons from 20 Years of Venture Capital (Roelof Botha, Managing Partner & Steward at Sequoia Capital)

@nicholas1h ago

POD

How AI Will Enhance Human Potential, Not Replace It (Reid Hoffman)

@nicholas1h ago

POD

When Science Fiction Becomes Reality (Josh Wolfe, Co-Founder of Lux Capital)

@nicholas1h ago

POD

Introducing The Generalist Podcast

@nicholas1h ago

POD

Creating Stars in a Bottle: The Race to Commercialize Fusion Energy (Vinod Khosla & Bob Mumgaard)

@nicholas1h ago

POD

Antimemetics: Why Some Ideas Resist Spreading (Nadia Asparouhova, Writer & Researcher)

@nicholas1h ago

POD

How Anduril Is Reimagining the Defense Industry: Faster Tech, Ethical AI, and a New Kind of Deterrence (Trae Stephens, Co-Founder & Executive Chairman of Anduril)

@nicholas1h ago

POD

The Semiconductor Century with Chris Miller (Author of “Chip War”)

@nicholas1h ago

POD

Are We Alone In The Universe? Sara Seager on Exoplanets, Venus, and the Hunt for Alien Life (Astrophysicist and Planetary Scientist at MIT)

@nicholas1h ago

POD

Existential Risk and the Future of Humanity: Lessons from AI, Pandemics, and Nuclear Threats (Toby Ord, Author of "The Precipice")

@nicholas1h ago

POD

Why the Real Computer Revolution Never Happened (Alan Kay & Anjan Katta)

@nicholas1h ago

POD

The Decade of Data (Tomasz Tunguz)

@nicholas1h ago

POD

No Rivals

@nicholas1h ago

POD

The Future of Crypto: Stablecoins, AI Integration, and the Path to Mass Adoption (Jesse Walden, Founder & Managing Partner at Variant)

@nicholas1h ago

POD

Inside General Catalyst’s $1B+ Bet on Fixing Healthcare (Hemant Taneja, CEO & Managing Partner)

@nicholas1h ago

POD

AI Agents Are Here: What They Can Already Do—and What’s Next (Stanislas Polu & Harrison Chase)

@nicholas1h ago

POD

Reviving Forgotten Technologies: How Airships, Supersonic Flight, and Geothermal Energy Could Transform Our World (Eli Dourado, Head of Strategic Investments at Astera Institute)

@nicholas1h ago

POD

What Makes Something Alive? Assembly Theory and the Origins of Life (Sara Walker, Theoretical Physicist)

@nicholas1h ago

POD

Building Beautiful Homes with Robots: The Future of Construction (Salar al Khafaji, CEO & Founder of Monumental)

@nicholas1h ago

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Can Humans Stay Smart in the Age of AI? (David Krakauer, President of the Santa Fe Institute)

@nicholas1h ago

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How to be Agentic in the Age of AI (Cate Hall, CEO of Astera)

@nicholas1h ago

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"This feels like 1996": Why a16z's Martin Casado believes the AI boom still has years to run (General Partner)

@nicholas1h ago

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Why Psychedelics Might Be the Breakthrough That PTSD Patients Need (Kevin Ryan, The Godfather of NYC Tech)

@nicholas1h ago

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The Trillion-Dollar AI Hardware Opportunity (Navin Chaddha, Managing Partner at Mayfield)

@nicholas1h ago

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Joey Krug on Prediction Markets, Crypto Treasuries & the Next Era of On-Chain Finance (Partner at Founders Fund)

@nicholas1h ago

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How Do You Build a New Singapore? Inside Próspera’s Bet on Private Governance (Erick Brimen, Founder & CEO)

@nicholas1h ago

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How a Solo Founder is Reshaping Global Finance (Parth Garg, CEO of Aspora)

@nicholas1h ago

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Programming Sunlight: How Reflect Orbital Is Building Satellites to Redirect Light From Space (Ben Nowack, Founder & CEO)

@nicholas1h ago

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Nothing’s Carl Pei on Building a $1B Smartphone Company, Why He Left OnePlus After 10 Days of Retirement, and Why He Thinks About Death Every Week

@nicholas1h ago

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Why Being a Generalist VC Is a Competitive Advantage (Aydin Senkut, Founder & Managing Partner at Felicis Ventures)

@nicholas1h ago

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The Private Company Bringing Nuclear Enrichment Back to America (Scott Nolan, CEO of General Matter)

@nicholas1h ago

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How a 20-Person Startup Won Gold at the Math Olympiad—Tying With OpenAI & DeepMind (Tudor Achim, CEO of Harmonic)

@nicholas1h ago

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“Our Goal Is to Build an Electrical Engineer.” (Davide Asnaghi, Co-Founder & CEO of Diode)

@nicholas1h ago

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The Future Of Drug Discovery Is 4 Billion Years Old (Viswa Colluru, Founder & CEO at Enveda)

@nicholas1h ago

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30% Of Network Engineers Are Retiring. What Happens Next? (Anil Varanasi, Co-Founder & CEO of Meter)

@nicholas1h ago

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Investing Like A Mystic: How Cyan Banister Finds Outliers (Co-Founder of Long Journey Ventures)

@nicholas1h ago

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How Bolt Survived An 85% Revenue Crash And Became Europe's Ride-Hailing Champion (Markus Villig, Founder & CEO)

@nicholas1h ago

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America’s Electric Power Grid Is Broken. This Startup Is Trying to Fix It. (Zach Dell, co-founder & CEO of Base)

@nicholas1h ago

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Biological Time Travel: How Cryopreservation Could Transform Medicine (Laura Deming, CEO & co-founder of Until)

@nicholas1h ago

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Why One Superintelligence Is More Dangerous Than a Thousand (Vincent Weisser, CEO & Co-Founder of Prime Intellect)

@nicholas1h ago

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Why Robots Still Struggle With Simple Tasks (And What Might Finally Change That) | Karol Hausman, Co-Founder & CEO of Physical Intelligence

@nicholas1h ago

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Everyone Is Betting on Bigger LLMs. She's Betting They're Fundamentally Wrong. (Eve Bodnia, Founder & CEO of Logical Intelligence)

@nicholas1h ago

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